PRICKLE2 Antibody

Datasheet

Citations (2)

Code	CSB-PA773783ESR1HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA773783ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA773783ESR1HU at dilution of 1:100
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Product Details
Citations
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PRICKLE2 Polyclonal antibody

Uniprot No.

Q7Z3G6

Target Names

PRICKLE2

Alternative Names

EPM5 antibody; PRIC2 antibody; PRIC2_HUMAN antibody; Prickle homolog 2 (Drosophila) antibody; Prickle planar cell polarity protein 2 antibody; prickle-like 2 (Drosophila) antibody; prickle-like 2 antibody; Prickle-like protein 2 antibody; PRICKLE2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Prickle-like protein 2 protein (615-844AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

Nasal polyps show decreased mucociliary transport despite vigorous ciliary beating TN Nguyen,Brazilian journal of otorhinolaryngology,2024
Mucociliary transport velocity is decreased in nasal polyp mucosae despite vigorous ciliary beating TN Nguyen,/,2022

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 2 reviews

Submit a Review here

Applications : Immunohistochemical staining

Sample type: tissues

Review: Frizzled6. Weak and moderate fluorescence are observed on the surface and in the basal layer of the turbinate epithelium, respectively, while the nasal polyp shows no immunoreactivity.

By Anonymous

Applications : Fluorescence immunohistochemistry

Sample type: tissue

Review: Prickle2. Moderate and weak fluorescence are seen on the surface of the turbinate mucosa and nasal polyp, respectively.

By Anonymous

Target Background

Gene References into Functions

2 autism-spectrum-disorder patients had distinct, paternally inherited, heterozygous, non-synonymous PRICKLE2 variants (p.E8Q and p.V153I) shared by their affected siblings. These variants had deficits in morphological and electrophysiological assays. PMID: 23711981

Involvement in disease

PRICKLE2 mutations have been found in patients with myoclonic epilepsy but involvement of this gene in pathogenesis is under debate since some of the patients also carry POLG mutations.

Subcellular Location

Nucleus membrane.

Protein Families

Prickle / espinas / testin family

Tissue Specificity

Expressed in brain, eye and testis. Additionally in fetal brain, adult cartilage, pancreatic islet, gastric cancer and uterus tumors.

Database Links

HGNC: 20340

OMIM: 608501

KEGG: hsa:166336

STRING: 9606.ENSP00000295902

UniGene: Hs.148105

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Wnt signaling pathway

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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