PSMB6 Antibody

Datasheet

Code	CSB-PA018884GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

P28072

Target Names

PSMB6

Alternative Names

DELTA antibody; LMPY antibody; Macropain delta chain antibody; MGC5169 antibody; Multicatalytic endopeptidase complex delta chain antibody; Proteasome (prosome macropain) subunit beta type 6 antibody; Proteasome beta 6 subunit antibody; Proteasome catalytic subunit 1 antibody; Proteasome delta chain antibody; Proteasome subunit beta 6 antibody; Proteasome subunit beta type 6 antibody; Proteasome subunit beta type-6 antibody; Proteasome subunit delta antibody; Proteasome subunit Y antibody; PSB6_HUMAN antibody; PSMB6 antibody; PSY large multifunctional protease Y antibody; Y antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human PSMB6

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB6 displays a peptidylglutamyl-hydrolizing activity also termed postacidic or caspase-like activity, meaning that the peptides bond hydrolysis occurs directly after acidic residues.

Gene References into Functions

results indicate ZAG as a possible predictive marker of Gleason grade. The inverse association between grade and tissue expression with a rising serum protein level is similar to that seen with prostate-specific antigen. In addition, the results for both ZAG and PSMB-6 highlight the challenges in trying to associate the protein levels in serum with tissue expression PMID: 20661134

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

Peptidase T1B family

Database Links

HGNC: 9543

OMIM: 600307

KEGG: hsa:5694

STRING: 9606.ENSP00000270586

UniGene: Hs.77060

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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