RAD54B Antibody

1. High RAD54B expression is associated with hepatoma. PMID: 29956808
2. Review of structural aspects of RAD54B, molecular functions associated with its cellular roles in preventing genome instability, and how aberrant function contributes to oncogenesis. PMID: 28295846
3. RAD54B expression has potential to serve as a novel prognostic biomarker, particularly for distant recurrence in colorectal cancer PMID: 26046797
4. Patients with expression of both FEN1 and RAD54B were prone to have advanced nodal involvement and significantly poor prognosis. PMID: 26431531
5. The scaffolding function of Rad54B dynamically regulates the maintenance of genome integrity by limiting checkpoint strength. PMID: 25384516
6. support a model in which RAD54L and RAD54B counteract genome-destabilizing effects of direct binding of RAD51 to dsDNA in tumor cells PMID: 25765654
7. RAD54B-deficient cells are selectively killed relative to controls via siRNA-based silencing of SOD1 PMID: 24002644
8. RAD54B and GREB1 gene polymorphisms may not be associated with PCOS in the Han Chinese population. PMID: 23876972
9. These results suggest that hINO80 assists double-strand break repair by positively regulating the expression of the Rad54B and XRCC3 genes. PMID: 20687897
10. Rad54B is a DNA-dependent ATPase and has biochemical properties different from its structural homolog in yeast, Tid1/Rdh54 PMID: 11884632
11. Rad54B enhanced the DNA strand-exchange activity of Dmc1 by stabilizing the Dmc1-single-stranded DNA complex. PMID: 16945962
12. the loss of heterozygosity (LOH) in the 8q12-q24.1 chromosomal region, containing RAD54B gene isn't predictive for breast cancer PMID: 17585536
13. S100A11 targets Rad54B to sites of DNA DSB repair sites and has a role in p21-based regulation of cell cycle PMID: 18463164
14. RAD54B binding may affect the quaternary structure of DMC1. PMID: 18718930
15. RAD54B-deficient human colorectal cancer cells are sensitive to synthetic lethal killing by reduced FEN1 expression, while isogenic RAD54B proficient cells are not PMID: 19218431

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HGNC: 17228

OMIM: 604289

KEGG: hsa:25788

STRING: 9606.ENSP00000336606

UniGene: Hs.30561