RPL35A Antibody

Code CSB-PA020248LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human lymphoid tissue using CSB-PA020248LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA020248LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RPL35A Polyclonal antibody
Uniprot No.
Target Names
RPL35A
Alternative Names
60S ribosomal protein L35a antibody; Cell growth-inhibiting gene 33 protein antibody; DBA5 antibody; L35A antibody; Ribosomal Protein L35a antibody; RL35A_HUMAN antibody; RPL35A antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human 60S ribosomal protein L35a protein (1-110AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The RPL35A Antibody (Product code: CSB-PA020248LA01HU) is Non-conjugated. For RPL35A Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA020248LB01HU RPL35A Antibody, HRP conjugated ELISA
FITC CSB-PA020248LC01HU RPL35A Antibody, FITC conjugated
Biotin CSB-PA020248LD01HU RPL35A Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site.
Gene References into Functions
  1. We identified 85 overlapping deletions, of which six included the RPL35A gene and all should be had Diamond-Blackfan anemia (DBA).we sequenced the remaining RNF168 gene and examined her fibroblast culture for a DNA double strand break repair deficiency. These results were normal, indicating that the immunodeficiency is unlikely to result from a RNF168 deficiency. PMID: 28432740
  2. Studies identified deletions at known Diamond-Blackfan anemia (DBA)-related ribosomal protein gene loci in 17% (9 of 51) of patients without an identifiable mutation, including RPS19, RPS17, RPS26, and RPL35A. PMID: 22045982
  3. Inhibition of cell death by ribosomal protein L35a. PMID: 12175552
  4. analysis of 2 Diamond-Blackfan anemia (DBA) patients with chromosome 3q deletions identified RPL35A as a potential DBA gene PMID: 18535205
Involvement in disease
Diamond-Blackfan anemia 5 (DBA5)
Protein Families
Eukaryotic ribosomal protein eL33 family
Database Links

HGNC: 10345

OMIM: 180468

KEGG: hsa:6165

STRING: 9606.ENSP00000393393

UniGene: Hs.529631

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