SEC22B Antibody

Code CSB-PA020945LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SEC22B Polyclonal antibody
Uniprot No.
Target Names
SEC22B
Alternative Names
SEC22B; SEC22L1; Vesicle-trafficking protein SEC22b; ER-Golgi SNARE of 24 kDa; ERS-24; ERS24; SEC22 vesicle-trafficking protein homolog B; SEC22 vesicle-trafficking protein-like 1
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Vesicle-trafficking protein SEC22b protein (2-194AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SEC22B Antibody (Product code: CSB-PA020945LA01HU) is Non-conjugated. For SEC22B Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA020945LB01HU SEC22B Antibody, HRP conjugated ELISA
FITC CSB-PA020945LC01HU SEC22B Antibody, FITC conjugated
Biotin CSB-PA020945LD01HU SEC22B Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
Gene References into Functions
  1. the target gene SEC22B regulated by miRNA-206 may play a key role in the progression and development of AD. PMID: 26082458
  2. Suggest that close apposition of the ER and plasma membrane mediated by Sec22b and plasma membrane syntaxins generates a non-fusogenic SNARE bridge contributing to plasma membrane expansion, probably through non-vesicular lipid transfer. PMID: 24705552
  3. DrrA activation of the Rab1 GTPase on plasma membrane-derived organelles stimulated the tethering of endoplasmic reticulum-derived vesicles, resulting in vesicle fusion through the pairing of Sec22b with the plasma membrane syntaxin proteins. PMID: 22264512
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus, cis-Golgi network membrane. Golgi apparatus, trans-Golgi network membrane. Melanosome.
Protein Families
Synaptobrevin family
Database Links

HGNC: 10700

OMIM: 604029

KEGG: hsa:9554

UniGene: Hs.632438

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