SLC25A2 Antibody

Code CSB-PA964037
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA964037(SLC25A2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
SLC25A2
Alternative Names
SLC25A2; ORNT2; Mitochondrial ornithine transporter 2; Solute carrier family 25 member 2
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human SLC25A2
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:20-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix.
Gene References into Functions
  1. characterized mutations of the proposed substrate binding site in ORC1 and ORC2; demonstrated that the residue at position 179 in the 2 soforms is largely responsible for the difference in their substrate specificity;concluded that Arg-179 is a key residue in the opening of the carrier to the matrix side PMID: 22262851
  2. expression, reconstitution, functional characterization, and tissue distribution of two human isoforms ORC1 and ORC2 PMID: 12807890
  3. Here we identify a new intronless gene, ORNT2, located on chromosome 5. PMID: 12948741
Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein Families
Mitochondrial carrier (TC 2.A.29) family
Tissue Specificity
Expressed in liver, kidney, pancreas and cultured fibroblasts.
Database Links

HGNC: 22921

OMIM: 608157

KEGG: hsa:83884

STRING: 9606.ENSP00000239451

UniGene: Hs.97647

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