SLC25A3 Antibody

Code CSB-PA265169
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA265169(SLC25A3 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA265169(SLC25A3 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
SLC25A3
Alternative Names
mitochondrial antibody; Mitochondrial phosphate carrier protein antibody; MPCP_HUMAN antibody; OK/SW cl.48 antibody; PHC antibody; Phosphate carrier protein antibody; Phosphate carrier protein mitochondrial antibody; Phosphate carrier protein mitochondrial precursor antibody; Phosphate transport protein antibody; PTP antibody; Slc25a3 antibody; Solute carrier family 25 member 3 antibody; Solute carrier family 25 mitochondrial carrier phosphate carrier member 3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide of Human SLC25A3
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP).
Gene References into Functions
  1. these results indicate that PiC depletion may need to be profound (>85%) to substantially affect maximal oxphos and that pathogenesis associated with PiC depletion or loss of function may be independent of phosphate limitation when ATP requirements are not high. PMID: 27780865
  2. Compares and contrasts all the known human SLC25A* genes and includes functional information. PMID: 23266187
  3. An analysis of the promoter region of the human mitochondrial phosphate transporter, including its activation and inhibition domains, is reported. PMID: 15984930
  4. SLC25A3 protein deficiency is associated with lactic acidosis, hypertrophic cardiomyopathy, and muscular hypotonia PMID: 17273968
Involvement in disease
Mitochondrial phosphate carrier deficiency (MPCD)
Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein Families
Mitochondrial carrier (TC 2.A.29) family
Database Links

HGNC: 10989

OMIM: 600370

KEGG: hsa:5250

STRING: 9606.ENSP00000228318

UniGene: Hs.290404

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