SLC30A4 Antibody

1. There was a significant increase in protein levels of ZnT4 in the prefrontal cortex in Major depression disorder, relative to control subjects. PMID: 27661418
2. TRPML1 works in concert with ZnT4 to regulate zinc translocation between the cytoplasm and lysosomes. PMID: 23368743
3. The loss of ZnT4 in airway inflammation contributes to airway epithelium vulnerability in diseases such as asthma. PMID: 22254085
4. Genomic localization, organization; exclusion in variants of acrodermatitis enteropathica. PMID: 11686514
5. not responsible for acrodermatitis enteropathica in Japanese families PMID: 11935329
6. hZnT4 is constitutively expressed in the human breast and may be one of the several members of the ZnT family involved in the transport of zinc into milk PMID: 11988082
7. The hZnT4 protein did not co-localise with intracellular free zinc pools, suggesting that hZnT4 is not involved in transport of zinc into vesicles destined for secretion into milk. PMID: 12743795
8. decreased intensity of ZnT4 immunoreactivity occurred in the progression from benign to invasive localized prostate cancer and to metastatic disease PMID: 12955079
9. Decreased hZnT-4 expression is associated with prostate tissue abnormalities independent of total cellular zinc content. PMID: 14968438
10. findings implicate a role for ZnT(4) in mast cell Zn homeostasis and suggest that granule pools of Zn may be distinct from those regulating activation of procaspase-3 and NF-kappaB. PMID: 15187159
11. Our results show that Zn transporter-4 and Zn transporter-6 are significantly (P<0.05) increased in hippocampus/parahippocampal gyrus of early Alzheimer's disease and Alzheimer's disease subjects. PMID: 16580781
12. hZnT-4 is found in the plasma membrane. It is most highly expressed in Molt-4 cells, up-regulated after treatment with phytohemagglutinin & is responsible for the measured decrease of intracellular zinc content after high zinc exposure. PMID: 17971500
13. Data show that ZNT4 is extensively present in the Abeta-positive plaques in the cortex of human AD brains. PMID: 18639746

Show More

Hide All

HGNC: 11015

OMIM: 602095

KEGG: hsa:7782

STRING: 9606.ENSP00000261867

UniGene: Hs.162989