SLC6A11 Antibody

1. GAT-3 expression was selectively decreased in the central amygdala of alcohol-dependent people compared to those who died of unrelated causes. PMID: 29930131
2. GABA-transporter 3 was reduced by about 62% in severe hippocampal sclerosis samples PMID: 26212582
3. results suggest that GABA receptor signaling pathway was associated with the increased susceptibility to TD in Korean schizophrenic patients PMID: 23795861
4. Binding assays employing membrane preparations obtained from a stably GAT3 expressing HEK293 cell line and DDPM-1007 as nonlabeled GAT3 marker were performed. In these experiments specific binding of DDPM-1007 at GAT3 could be unambiguously detected. PMID: 23225341
5. The results suggest that GAT3 c.1572T may be one of the contributing factors with a modest effect on antiepileptic drug (AEDs) pharmacoresistance in the epileptic brain. PMID: 21776001
6. homology models of hGAT-2 and hGAT-3 were built and searched for (i) substrate conformation, (ii) prediction of substrate (inhibitor) interaction, and (iii) distinguishable allosteric Zn2+ inhibition by combining docking and MD calculations. PMID: 19450549

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HGNC: 11044

OMIM: 607952

KEGG: hsa:6538

STRING: 9606.ENSP00000254488

UniGene: Hs.655078