SLIT1 Antibody

Datasheet

Code	CSB-PA258249
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA258249(SLIT1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA258249(SLIT1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O75093

Target Names

SLIT1

Alternative Names

KIAA0813 antibody; MEGF 4 antibody; MEGF4 antibody; MGC164811 antibody; Multiple EGF-like domains protein 4 antibody; Multiple epidermal growth factor like domains 4 antibody; Multiple epidermal growth factor-like domains protein 4 antibody; OTTHUMP00000059392 antibody; SLIL 1 antibody; SLIL1 antibody; Slit 1 antibody; SLIT 3 antibody; Slit homolog 1 antibody; Slit homolog 1 protein antibody; Slit-1 antibody; Slit1 antibody; SLIT1_HUMAN antibody; SLIT3 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide of Human SLIT1

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.

Gene References into Functions

Analysis of alternative splicing and conserved domains in human and mouse slit genes PMID: 12141424
evidence showing that Slit1 and Slit2 proteins are selective inhibitors and repellents for dorsally projecting, but not for ventrally projecting, cranial motor axons PMID: 16162649
In fetal and embryonic stem cell cultures Slit-1 inhibited neurite outgrowth. PMID: 16840550

Subcellular Location

Secreted.

Tissue Specificity

Predominantly expressed in adult forebrain. Expressed in fetal brain, lung and kidney.

Database Links

HGNC: 11085

OMIM: 603742

KEGG: hsa:6585

STRING: 9606.ENSP00000266058

UniGene: Hs.632082

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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