SMU1 Antibody

Code CSB-PA021858GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SMU1
Alternative Names
SMU1 antibody; WD40 repeat-containing protein SMU1 antibody; Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1 antibody; N-terminally processed] antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SMU1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in pre-mRNA splicing as a component of the spliceosome. Regulates alternative splicing of the HSPG2 pre-mRNA. Required for normal accumulation of IK. Required for normal mitotic spindle assembly and normal progress through mitosis.; (Microbial infection) Required, together with IK, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles.
Gene References into Functions
  1. Data suggest that two human spliceosomal factors, SMU1 and RED, are recruited to control expression and alternative splicing of viral exportins via PB2 (polymerase PB2) of influenza A virus (H3N2) and are required for efficient viral multiplication. PMID: 24945353
  2. Data suggest that Smu1 participates in the protection of genomic integrity by negatively regulating the process of DNA synthesis. PMID: 23727573
Subcellular Location
Cytoplasm. Nucleus. Nucleus speckle.
Protein Families
WD repeat SMU1 family
Database Links

HGNC: 18247

OMIM: 617811

KEGG: hsa:55234

STRING: 9606.ENSP00000380336

UniGene: Hs.655351

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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