STX5 Antibody

1. Expression of the Syn5 K270R mutant in cells impairs post-mitotic Golgi reassembly PMID: 27404360
2. Together, these data strongly suggest that syntaxin 5-mediated retrograde transport to the Golgi apparatus is a broadly conserved feature of adeno-associated virus trafficking. PMID: 25410859
3. Stx5 might play a role in modulating VLDL-R physiology by participating in an abrasively described or completely novel Golgi-bypass pathway. PMID: 23701949
4. serum anti-STX5 autoantibody, which was discovered by a proteomic approach, is a potential new serum marker for the diagnosis of endometriosis. PMID: 21715015
5. Depletion of syntaxin-5 complex components results in the accumulation of autophagosomes as a result of lysosomal dysfunction, leading to decreased degradation of autophagic substrates. PMID: 21242315
6. Syx5 is required for the maintenance of the Golgi structures but may not play a major role in the transport of vesicles carrying proteins between the ER and the Golgi compartment. PMID: 16081076
7. hypothesize that syntaxin 5 also has trafficking-independent functions PMID: 17389686
8. depletion of GM130 by RNA interference slows the rate of ER to Golgi trafficking in vivo; interactions of GM130 with syntaxin 5 and Rab1 are regulated by mitotic phosphorylation PMID: 18167358
9. Study shows that the SM protein, Sly1, interacts directly with the conserved oligomeric Golgi (COG) tethering complex; Sly1-COG interaction is mediated by the Cog4 subunit, which also interacts with Syntaxin 5 through a different binding site. PMID: 19536132

Show More

Hide All

HGNC: 11440

OMIM: 603189

KEGG: hsa:6811

STRING: 9606.ENSP00000294179

UniGene: Hs.654602