SUN5 Antibody

Datasheet

Code	CSB-PA192614
Size	US$297
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Image	Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using at dilution 1/70. Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/70.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SUN5 Polyclonal antibody

Uniprot No.

Q8TC36

Target Names

SUN5

Alternative Names

SUN5; SPAG4L; TSARG4; SUN domain-containing protein 5; Sad1 and UNC84 domain-containing protein 5; Sperm-associated antigen 4-like protein; Testis and spermatogenesis-related gene 4 protein

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of Human Sad1 and UNC84 domain containing 5

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:50-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Plays an essential role in anchoring sperm head to the tail. Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope.

Gene References into Functions

The contribution of SUN5 mutations to acephalic spermatozoa might not be as high as described previously. PMID: 29331481
Results, together with those of the previous study, show that SUN5 is required for the formation of the sperm head-tail junction and male fertility. PMID: 28541472
results demonstrate that biallelic SUN5 mutations cause male infertility due to autosomal-recessive acephalic spermatozoa syndrome PMID: 27640305
SPAG4L may play an important role in the meiotic stage of spermatogenesis PMID: 21711156

Involvement in disease

Spermatogenic failure 16 (SPGF16)

Subcellular Location

Nucleus inner membrane; Single-pass membrane protein. Golgi apparatus.

Tissue Specificity

Sperm (at protein level). Widely expressed. Conflictingly shown to be specifically expressed in testis.

Database Links

HGNC: 16252

OMIM: 613942

KEGG: hsa:140732

STRING: 9606.ENSP00000348496

UniGene: Hs.375186

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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