TDRD9 Antibody

Datasheet

Code	CSB-PA850866LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA850866LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TDRD9 Polyclonal antibody

Uniprot No.

Q8NDG6

Target Names

TDRD9

Alternative Names

C14orf75 antibody; chromosome 14 open reading frame 75 antibody; DKFZp434N0820 antibody; FLJ36164 antibody; HIG 1 antibody; Hypoxia inducible HIG 1 antibody; MGC135025 antibody; NET54 antibody; Putative ATP dependent RNA helicase TDRD9 antibody; Putative ATP-dependent RNA helicase TDRD9 antibody; TDRD 9 antibody; Tdrd9 antibody; TDRD9_HUMAN antibody; Tudor domain containing 9 antibody; Tudor domain containing protein 9 antibody; Tudor domain-containing protein 9 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Putative ATP-dependent RNA helicase TDRD9 protein (286-585AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TDRD9 Antibody (Product code: CSB-PA850866LA01HU) is Non-conjugated. For TDRD9 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA850866LB01HU	TDRD9 Antibody, HRP conjugated	ELISA
FITC	CSB-PA850866LC01HU	TDRD9 Antibody, FITC conjugated
Biotin	CSB-PA850866LD01HU	TDRD9 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

ATP-binding RNA helicase required during spermatogenesis. Required to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Acts downstream of piRNA biogenesis: exclusively required for transposon silencing in the nucleus, suggesting that it acts as a nuclear effector in the nucleus together with PIWIL4.

Gene References into Functions

first report of a recessive deleterious mutation in TDRD9 in humans; study demonstrates that non-obstructive azoospermia can be caused by a mutation in TDRD9 PMID: 28536242

Involvement in disease

Defects in TDRD9 may be a cause of non-obstructive azoospermia, a disorder characterized by the absence of sperm. Female fertility is not affected.

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

DEAD box helicase family, DEAH subfamily

Database Links

HGNC: 20122

KEGG: hsa:122402

STRING: 9606.ENSP00000387303

UniGene: Hs.21454

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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