TESPA1 Antibody

Datasheet

Code	CSB-PA012205LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA012205LA01HU at dilution of 1:100 Immunofluorescent analysis of A549 cells using CSB-PA012205LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TESPA1 Polyclonal antibody

Uniprot No.

A2RU30

Target Names

TESPA1

Alternative Names

TESPA1 antibody; KIAA0748 antibody; HSPC257Protein TESPA1 antibody; Thymocyte-expressed positive selection-associated protein 1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Protein TESPA1 protein (251-521AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TESPA1 Antibody (Product code: CSB-PA012205LA01HU) is Non-conjugated. For TESPA1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA012205LB01HU	TESPA1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA012205LC01HU	TESPA1 Antibody, FITC conjugated
Biotin	CSB-PA012205LD01HU	TESPA1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.

Gene References into Functions

Tespa1 functions in T cell development and the regulation of TCR-induced Ca(2+) signalling through IP3R1 PMID: 28598420
Tespa1 hay have a role in susceptibility but not severity of rheumatoid arthritis in the Zhejiang Han population in China PMID: 25736038
The TESPA1 gene was found to not be involved in ankylosing spondylitis in a Chinese population. PMID: 24893580
Tespa1 is post-translationally modified upon intracellular divalent calcium-ion Ca2+ increase in thymocytes. PMID: 23541577
Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux. PMID: 23501103

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Subcellular Location

Cytoplasm. Endoplasmic reticulum membrane.

Database Links

HGNC: 29109

OMIM: 615664

KEGG: hsa:9840

STRING: 9606.ENSP00000312679

UniGene: Hs.33187

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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