TRAK1 Antibody

1. Data show that the ADP-ribosylation factor 6 (Arf6)-trafficking kinesin protein 1 (trak1) promote the anterograde trafficking of mitochondria. PMID: 29992963
2. This study confirms the role of TRAK1 in mitochondrial dynamics and constitutes the first report of this gene in association with a severe neurodevelopmental disorder. PMID: 28364549
3. This study showed that the TRAK1 was prevalently localized in axons of hippocampal and cortical neurons. PMID: 25653102
4. Data suggest that vitamin D receptor target genes (TRAK1; DUSP10, dual specificity phosphatase 10; NRIP1, nuclear receptor interacting protein 1; THBD, thrombomodulin) can be used as markers for individual's response to vitamin D3 supplements. PMID: 24975273
5. By mapping and mutating four key sites of GlcNAc addition in hMilton1 (hMilton1Qmut), study demonstrated that Milton is the key and essential substrate through which OGT inhibits mitochondrial motility. PMID: 24995978
6. Details of a robust association of DISC1 with mitochondrial transport complexes containing TRAK1 and Miro1. PMID: 24092329
7. The results of this study established a key role for mammalian TRAK1 proteins in axonal and dendritic targeting of mitochondria. PMID: 23395375
8. MGb2-Ag/TRAK1 may play an important role in the development of colorectal cancer (CRC) and may be a valuable prognostic indicator of CRC. PMID: 21573901
9. GRIF-1 and OIP106 have roles in protein and/or organelle transport in excitable cells in a manner analogous to glutamate receptor-interacting-protein 1 PMID: 15644324
10. Data show that Trak1 interacts with hepatocyte-growth-factor-regulated tyrosine kinase substrate (Hrs), an essential component of the endosomal sorting and trafficking machinery. PMID: 18675823
11. TRAK1/MGb2-Ag is a promising diagnostic marker for gastric cancer and may help to detect signet-ring cell carcinoma and mucinous adenocarcinoma PMID: 18986759

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HGNC: 29947

OMIM: 608112

KEGG: hsa:22906

STRING: 9606.ENSP00000328998

UniGene: Hs.535711