ULK4 Antibody

Code CSB-PA853394ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA853394ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA853394ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ULK4 Polyclonal antibody
Uniprot No.
Target Names
ULK4
Alternative Names
DKFZp 434E1822 antibody; DKFZp434E1822 antibody; FAM 7 C 1 antibody; FAM7C1 antibody; FLJ 20574 antibody; FLJ20574 antibody; REC 01035 antibody; REC01035 antibody; Serine/threonine-protein kinase ULK4 antibody; ULK 4 antibody; ULK4 antibody; ULK4_HUMAN antibody; Unc 51 like kinase 4 antibody; Unc 51 like kinase 4 (C. elegans) antibody; Unc-51-like kinase 4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Serine/threonine-protein kinase ULK4 protein (1-290AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as cell motility.
Gene References into Functions
  1. results indicate that genetic variations in LRP1 and ULK4 contribute to risk for presenting with an acute aortic dissection PMID: 27569546
  2. Our findings indicate that ULK4 is a rare susceptibility gene for schizophrenia. PMID: 24284070
  3. First identified as an ULK family kinase and predicted to be catalytically inactive. PMID: 12471243
  4. Single-nucleotide polymorphism rs1052501 in ULK4 gene is associated with monoclonal gammopathy of undetermined significance and multiple myeloma PMID: 22945773
Involvement in disease
Various anomalies in ULK4 gene have been reported for several cases of schizophrenia, schizophrenia plus bipolar disorder and autism. ULK4 gene has been proposed to be a rare susceptibility risk factor for a range of psychiatric diseases including schizophrenia.
Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily
Tissue Specificity
Expressed in the brain, mainly in postmitotic neurons, including GABAergic neurons, but not in astrocytes (at protein level).
Database Links

HGNC: 15784

OMIM: 617010

KEGG: hsa:54986

STRING: 9606.ENSP00000301831

UniGene: Hs.656192

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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