YAF2 Antibody

Code CSB-PA810297LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA810297LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human glioma using CSB-PA810297LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) YAF2 Polyclonal antibody
Uniprot No.
Target Names
YAF2
Alternative Names
MGC41856 antibody; YAF2 antibody; YAF2_HUMAN antibody; YY1-associated factor 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human YY1-associated factor 2 protein (1-204AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The YAF2 Antibody (Product code: CSB-PA810297LA01HU) is Non-conjugated. For YAF2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA810297LB01HU YAF2 Antibody, HRP conjugated ELISA
FITC CSB-PA810297LC01HU YAF2 Antibody, FITC conjugated
Biotin CSB-PA810297LD01HU YAF2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds to MYC and inhibits MYC-mediated transactivation. Also binds to MYCN and enhances MYCN-dependent transcriptional activation. Increases calpain 2-mediated proteolysis of YY1 in vitro. Component of the E2F6.com-1 complex, a repressive complex that methylates 'Lys-9' of histone H3, suggesting that it is involved in chromatin-remodeling.
Gene References into Functions
  1. These findings uncovered an apoptotic signaling cascade linking YAF2, PDCD5, and TP53 during genotoxic stress responses. PMID: 25603536
  2. YEAF1/RYBP and YAF-2 are functionally distinct members of a cofactor family for the YY1 and E4TF1/hGABP transcription factors. PMID: 11953439
Subcellular Location
Nucleus.
Database Links

HGNC: 17363

OMIM: 607534

KEGG: hsa:10138

UniGene: Hs.649195

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