ZNF175 Antibody

Datasheet

Code	CSB-PA026556LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA026556LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ZNF175 Polyclonal antibody

Uniprot No.

Q9Y473

Target Names

ZNF175

Alternative Names

OTK18 antibody; Zinc finger protein 175 antibody; Zinc finger protein OTK18 antibody; ZN175_HUMAN antibody; ZNF175 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Zinc finger protein 175 protein (1-711AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ZNF175 Antibody (Product code: CSB-PA026556LA01HU) is Non-conjugated. For ZNF175 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA026556LB01HU	ZNF175 Antibody, HRP conjugated	ELISA
FITC	CSB-PA026556LC01HU	ZNF175 Antibody, FITC conjugated
Biotin	CSB-PA026556LD01HU	ZNF175 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat-induced viral LTR promoter activity.

Gene References into Functions

Transcriptional suppressor OTK18 plays a role in macrophage control of viral replication during advanced HIV-1 infection. PMID: 14688346
OTK18/zinc finger protein 175 expression in brain mononuclear phagocytes is a signature for advanced HIV-1 encephalitis. PMID: 15081264
Plasma OTK18 levels are positively correlated to CD8 T-cell counts, independent of HIV-1 status. PMID: 18773297
These results suggest a role for OTK18 in innate immunity. PMID: 18776638
These data suggest that calpain and proteasome are involved in OTK18 endoproteolysis and degradation PMID: 19034669
HIV-1 induces OTK18 expression through a YIN-YANG-1 mediated manner in human macrophages PMID: 19034670
OTK18 may play a role in neurotrophin production and consequently support neuronal survival. PMID: 19247725

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Subcellular Location

Cytoplasm. Nucleus.

Protein Families

Krueppel C2H2-type zinc-finger protein family

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 12964

OMIM: 601139

KEGG: hsa:7728

STRING: 9606.ENSP00000262259

UniGene: Hs.119014

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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