ZPBP Antibody

Code CSB-PA866271LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZPBP Polyclonal antibody
Uniprot No.
Target Names
ZPBP
Alternative Names
ZPBP antibody; ZPBP1Zona pellucida-binding protein 1 antibody; Inner acrosomal membrane IAM38 antibody; Sp38 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Zona pellucida-binding protein 1 protein (45-351AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ZPBP Antibody (Product code: CSB-PA866271LA01HU) is Non-conjugated. For ZPBP Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA866271LB01HU ZPBP Antibody, HRP conjugated ELISA
FITC CSB-PA866271LC01HU ZPBP Antibody, FITC conjugated
Biotin CSB-PA866271LD01HU ZPBP Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization.
Gene References into Functions
  1. Data suggest that missense mutations exert a dominant-negative effect due to altered ZPBP1 protein folding and protein:protein interactions in the acrosome. PMID: 21911476
  2. Data show that loss of zona pellucida binding proteins 1 and 2 in the acrosomal matrix disrupts acrosome biogenesis and sperm morphogenesis. PMID: 17664285
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Peripheral membrane protein. Secreted.
Protein Families
Zona pellucida-binding protein Sp38 family
Tissue Specificity
Expressed specifically in testis.
Database Links

HGNC: 15662

OMIM: 608498

KEGG: hsa:11055

STRING: 9606.ENSP00000046087

UniGene: Hs.388841

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