pptr-1 Antibody

Code CSB-PA117597XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans pptr-1 Polyclonal antibody
Uniprot No.
Target Names
pptr-1
Alternative Names
pptr-1 antibody; W08G11.4Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1 antibody; Serine/threonine-protein phosphatase 2A 56kDa regulatory subunit pptr-1 antibody; Serine/threonine-protein phosphatase 2A regulatory subunit B' pptr-1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans pptr-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Probable regulatory subunit of serine/threonine-protein phosphatase let-92 which negatively regulates the insulin receptor signaling cascade composed of daf-2, age-1, akt-1, akt-2 and sgk-1 by promoting the dephosphorylation of akt-1 on 'Thr-350'. Negatively regulates several functions controlled by the insulin pathway including dauer formation, lifespan, fat storage and stress resistance. Plays a role in the asymmetric segregation of the P granule components during embryonic cell divisions but does not play an essential role in specifying germ cell fate. In adults, required to promote germ cell proliferation and differentiation when exposed to thermic stress.
Subcellular Location
Cytoplasm.
Protein Families
Phosphatase 2A regulatory subunit B56 family
Tissue Specificity
Expressed in pharynx, vulva and spermatheca.
Database Links

KEGG: cel:CELE_W08G11.4

STRING: 6239.W08G11.4

UniGene: Cel.6704

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