3S11 Antibody

Datasheet
Code CSB-PA311138XA01MGQ
Product Type Polyclonal Antibody
Uniprot No. P86095
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Micrurus surinamensis (Surinam coral snake) 3S11 protein
Raised in Rabbit
Species Reactivity Micrurus surinamensis (Surinam coral snake)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Three-finger toxin MS1 (Short neurotoxin MS1)
Immunogen Species Micrurus surinamensis (Surinam coral snake)
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to and inhibits the endogenous nicotinic acetylcholine receptors (nAChR) in human rhabdomyosarcoma TE 671 cell line with an IC(50) of 48.2 mM. This neurotoxin is lethal to mice by intraperitoneal injection and to zebrafish by injection at the back of the dorsolateral region.
Subcellular Location Secreted
Protein Families Snake three-finger toxin family, Short-chain subfamily, Type I alpha-neurotoxin sub-subfamily
Tissue Specificity Expressed by the venom gland.

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