sev Antibody

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Code	CSB-PA321102XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) sev Polyclonal antibody

Uniprot No.

P13368

Target Names

sev

Alternative Names

sev antibody; HD-265 antibody; CG18085Protein sevenless antibody; EC 2.7.10.1 antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) sev protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Customer Reviews and Q&A

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Target Background

Function

Receptor for an extracellular signal required to instruct a cell to differentiate into an R7 photoreceptor. The ligand for sev is the boss (bride of sevenless) protein on the surface of the neighboring R8 cell.

Gene References into Functions

We show that Rap1 activity induces and/or maintains the formation of the apical domain of developing photoreceptor cells and that this event correlates with the apical accumulation and activity of SEV in presumptive R7 cells. PMID: 24899161
Sevenless (Sev), is required to ensure that the niche develops in the anterior region of the male embryonic gonads PMID: 17609117
Possibility of conserved Sevenless signaling controlled patterning processes in endopterygote insects. PMID: 18392882

Subcellular Location

Cell membrane; Single-pass membrane protein.

Protein Families

Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily

Database Links

KEGG: dme:Dmel_CG18085

STRING: 7227.FBpp0073249

Promotions

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Service

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sev Antibody

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