fbpA Antibody

Code CSB-PA978354XA01FQW
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Product Details

Full Product Name
Rabbit anti-Mycobacterium leprae (strain TN) fbpA Polyclonal antibody
Uniprot No.
Target Names
fbpA
Alternative Names
fbpA antibody; ML0097Diacylglycerol acyltransferase/mycolyltransferase Ag85A antibody; DGAT antibody; EC 2.3.1.122 antibody; EC 2.3.1.20 antibody; Acyl-CoA:diacylglycerol acyltransferase antibody; Antigen 85 complex A antibody; 85A antibody; Ag85A antibody; Fibronectin-binding protein A antibody; Fbps A antibody
Raised in
Rabbit
Species Reactivity
Mycobacterium leprae (strain TN)
Immunogen
Recombinant Mycobacterium leprae (strain TN) fbpA protein
Immunogen Species
Mycobacterium leprae (strain TN)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM. FbpA mediates triacylglycerol (TAG) formation with long-chain acyl-CoA as the acyl donor and 1,2-dipalmitoyl-sn-glycerol (1,2-dipalmitin) as the acyl acceptor. It has a preference for C26:0-CoA over C18:1-CoA.
Subcellular Location
Secreted, cell wall. Cytoplasm.
Protein Families
Mycobacterial A85 antigen family
Database Links

KEGG: mle:ML0097

STRING: 272631.ML0097

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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