Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ABCG40 Polyclonal antibody

Uniprot No.

Q9M9E1

Target Names

ABCG40

Alternative Names

ABCG40 antibody; PDR12 antibody; PDR9 antibody; At1g15520 antibody; T16N11.3ABC transporter G family member 40 antibody; ABC transporter ABCG.40 antibody; AtABCG40 antibody; Pleiotropic drug resistance protein 12 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana ABCG40 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Target Background

Function

High affinity abscisic acid (ABA) transporter that mediates the import of ABA, with a preference for (+)-ABA, through the plasma membrane, especially in guard cells, and is involved in the intercellular and intracellular ABA signaling pathways leading, for example, to stomatal closure, thus conferring drought tolerance. Together with ABCG30, import into the embryo the ABA delivered from the endosperm via ABCG25 and ABCG31-mediated export to suppress radicle extension and subsequent embryonic growth. May be a general defense protein. Functions as a pump to exclude Pb(2+) ions and/or Pb(2+)-containing toxic compounds from the cytoplasm. Contributes to Pb(2+) ions resistance. Confers some resistance to the terpene sclareol.; (Microbial infection) Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici.

Gene References into Functions

ABCG40 imports abscisic acid into the embryo, regulating seed germination. PMID: 26334616
Data suggest that Sorghum SbLRR2(Sb05g018800)appears to mediate Pb(II) tolerance through the elevation of AtPDR12 expression in transgenic Arabidopsis, thus activating a glutathione-independent mechanism for detoxification. PMID: 23877877
report the identification of the ATP-binding cassette (ABC) transporter Pleiotropic drug resistance transporter PDR12 (AtPDR12)/ABCG40 as a plasma membrane abscisic acid uptake transporter PMID: 20133880
PDR12 is an ABC transporter that contributes to lead resistance in Arabidopsis. [AtPDR12] PMID: 15923333

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

ABC transporter superfamily, ABCG family, PDR (TC 3.A.1.205) subfamily

Tissue Specificity

Mostly observed in inflorescence meristems relative to cauline leaves and developing siliques. Ubiquitous with higher levels in leaves, stems and flowers. Also present in primary and lateral roots. In seeds, mainly expressed in the embryo and, to a lesser

Database Links

KEGG: ath:AT1G15520

STRING: 3702.AT1G15520.1

UniGene: At.49303

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ABCG40 Antibody

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