ABCC5 Antibody

Code CSB-PA745280XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ABCC5 Polyclonal antibody
Uniprot No.
Target Names
ABCC5
Alternative Names
ABCC5 antibody; MRP5 antibody; At1g04120 antibody; F20D22.11ABC transporter C family member 5 antibody; ABC transporter ABCC.5 antibody; AtABCC5 antibody; EC 7.6.2.2 antibody; ATP-energized glutathione S-conjugate pump 5 antibody; Glutathione S-conjugate-transporting ATPase 5 antibody; Multidrug resistance-associated protein 5 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana ABCC5 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Pump for glutathione S-conjugates. Involved in regulation of K(+) and Na(+) cell content. Mediates resistance to NaCl and Li(+), confers sensitivity to sulfonylurea drugs such as glibenclamide (inducer of stomatal opening), and required for stomatal opening regulation by auxin, abscisic acid (ABA) and external Ca(2+). Transports oestradiol-17-(beta-D-glucuronide) (E(2)17G). Involved in the root auxin content regulation that controls the transition from primary root elongation to lateral root formation. Plays a role in ABA-mediated germination inhibition. High-affinity inositol hexakisphosphate transporter that plays a role in guard cell signaling and phytic acid storage. Required for phytic acid accumulation in developing seeds. Phytic acid is the primary storage form of phosphorus in cereal grains and other plant seeds.
Gene References into Functions
  1. Data demonstrate that AtMRP5 encodes a specific and high affinity ATP-dependent inositol hexakisphosphate transporter that is sensitive to inhibitors of ABC transporters. PMID: 19797057
  2. AtMRP5 ABC transporter is a central regulator of guard cell ion channel during abscisic acid and Ca(2+) signal transduction in guard cells PMID: 17098742
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
ABC transporter superfamily, ABCC family, Conjugate transporter (TC 3.A.1.208) subfamily
Tissue Specificity
Ubiquitous, mostly in vascular tissues and epidermis, including guard cells.
Database Links

KEGG: ath:AT1G04120

STRING: 3702.AT1G04120.1

UniGene: At.5395

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