ACD6 Antibody

Code CSB-PA928987XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ACD6 Polyclonal antibody
Uniprot No.
Target Names
ACD6
Alternative Names
ACD6 antibody; At4g14400 antibody; dl3240w antibody; FCAALL.190Protein ACCELERATED CELL DEATH 6 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana ACD6 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Dose-dependent activator of the defense response against virulent pathogens, including bacteria, fungi and oomycetes, that acts in a positive feedback loop with the defense signal salicylic acid (SA). Regulates the salicylic acid (SA) signaling pathway leading to cell death and modulating cell fate (e.g. cell enlargement and/or cell division). In response to SA signaling, triggers the accumulation of FLS2 at the plasma membrane, thus priming defenses. Involved in SA-dependent freezing signaling and tolerance.
Gene References into Functions
  1. NLR gene can mask the activity of an ACD6 autoimmune allele in natural A. thaliana populations, thereby linking different arms of the plant immune system. PMID: 30235212
  2. Data indicate protein kinases FLS2 and BAK1 contribute to autoimmune signaling in ACCELERATED CELL DEATH6 (ACD6) L591F amino acid substitution. PMID: 25315322
  3. Salicylic acid signaling controls the maturation and localization of the arabidopsis defense protein ACCELERATED CELL DEATH6 PMID: 24923602
  4. Here we show instead that hybrid necrosis can be triggered by interactions between variants of a single gene, ACD6 (ACCELERATED CELL DEATH 6). PMID: 25010663
  5. The effects of mutation on the structure and function of ACD6 in response to salicylic acid and disease resistance are reported. PMID: 16297071

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Subcellular Location
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity
Basal expression requires light and salicylic acid (SA).
Database Links

KEGG: ath:AT4G14400

STRING: 3702.AT4G14400.1

UniGene: At.23891

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