Ance Antibody

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Code	CSB-PA611997XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) Ance Polyclonal antibody

Uniprot No.

Q10714

Target Names

Ance

Alternative Names

Ance antibody; Race antibody; CG8827 antibody; Angiotensin-converting enzyme antibody; EC 3.4.15.1 antibody; Dipeptidyl carboxypeptidase I antibody; Kininase II antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) Ance protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

May be involved in the specific maturation or degradation of a number of bioactive peptides. May play a role in the contractions of the heart, gut and testes, and in spermatid differentiation.

Gene References into Functions

Data report the crystal structures of human testis ACE (tACE) and a homologue of ACE, known as AnCE, from Drosophila melanogaster in complex with a selenium analogue of captopril. PMID: 21810173
ance may be required for the processing of a developmental peptide hormone or may function in concert with other peptidases to provide amino acids for the synthesis of adult proteins PMID: 12093364
Ance is required for spermatid differentiation. PMID: 12591244
ANCE, which shares many enzymatic properties with mammalian ACE, is also a product of the male accessory gland of D. melanogaster. PMID: 17921161

Subcellular Location

Secreted, extracellular space.

Protein Families

Peptidase M2 family

Tissue Specificity

Expressed in vesicular structures in spermatocytes and early spermatids (at protein level).

Database Links

KEGG: dme:Dmel_CG8827

STRING: 7227.FBpp0080129

UniGene: Dm.2157

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