acr-16 Antibody

Code CSB-PA574484XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans acr-16 Polyclonal antibody
Uniprot No.
Target Names
acr-16
Alternative Names
acr-16 antibody; Ce21 antibody; F25G6.3Acetylcholine receptor subunit alpha-type acr-16 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans acr-16 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. A subunit of the levamisole-insensitive nicotinic receptor.
Gene References into Functions
  1. Xenopus laevis RIC-3 is more effective than the homomeric human or C. elegans ric-3 protein in chaperoning the expression of nematode nicotinic receptor ACR-16. PMID: 22970690
  2. ACR-16-containing receptors account for all non-levamisole-sensitive nicotinic synaptic signaling at the C. elegans NMJ PMID: 15917232
Subcellular Location
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=The cam-1 protein is required for correct localization.
Protein Families
Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily
Tissue Specificity
Expressed in the body wall muscle.
Database Links

KEGG: cel:CELE_F25G6.3

STRING: 6239.F25G6.3a

UniGene: Cel.18045

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