acrR Antibody

Code CSB-PA359825XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) acrR Polyclonal antibody
Uniprot No.
Target Names
acrR
Alternative Names
acrR antibody; ybaH antibody; b0464 antibody; JW0453HTH-type transcriptional regulator AcrR antibody; Potential acrAB operon repressor antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) acrR protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Potential regulator protein for the acrAB genes.
Gene References into Functions
  1. Mutations of AcrR protein in chloramphenicol resistant Ecoli, isolated from diseased chickens, cause the overexpression of AcrA protein of the AcrAB multidrug efflux pump. Complementation with a plasmid-borne wild-type acrR gene reduces the expression level of AcrA protein in the mutants and partially restored antibiotic susceptibility. PMID: 29307119
  2. Studied the genome-wide target genes of E. coli AcrR in a DeltaacrR mutant strain by microarray analysis. Motility assays revealed that AcrR modulates swimming motility, but not swarming. PMID: 27558437
  3. PCR analysis of RNA from the wild-type, DeltaacrR, and acrR (+) strains showed that AcrR represses the transcription of marRAB and soxRS, and its own gene cluster, acrRAB. PMID: 25176444
  4. A palindrome operator sequence that binds the multidrug efflux regulator AcrR was determined. PMID: 17644067
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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