ADR1 Antibody

Code CSB-PA357064XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ADR1 Polyclonal antibody
Uniprot No.
Target Names
ADR1
Alternative Names
ADR1 antibody; YDR216W antibody; YD8142.16 antibody; YD8142B.08Regulatory protein ADR1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ADR1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for transcriptional activation of glucose-repressible alcohol dehydrogenase (ADH2).
Gene References into Functions
  1. Residues outside the canonical binding 14-3-3 motif are important for interaction with Bmh1. PMID: 24142105
  2. there is an important overlap between the targets of Rds2 and Adr1. PMID: 22687600
  3. Data show that Bmh binds to the Snf1-dependent transcription factor Adr1 and inhibits its transcriptional activity. PMID: 20855531
  4. Adr1 is required for optimal Cat8 binding at promoters with a poor match to the Cat8 binding consensus. PMID: 15743812
  5. over-expression of Adr1 can compensate for loss of Cat8 at many genes in terms of both activation and chromatin remodeling PMID: 18197247
  6. ADH2 expression was dependent on these factors with wild-type Adr1 PMID: 18250152
  7. Data show that a nonphosphorylatable Ser230Ala mutant was no longer Snf1 dependent for activation of Adr1-dependent genes and could suppress Cat8 dependence at genes coregulated by Adr1 and Cat8. PMID: 19398770
  8. Adr1 influenced the transcription levels of ETR1, but it did not alter the abundance of Etr1 protein. PMID: 19583790
  9. Loss of Med14 activity enhances expression of Adr1-dependent genes independently of Snf1. PMID: 19732343

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Subcellular Location
Nucleus.
Database Links

KEGG: sce:YDR216W

STRING: 4932.YDR216W

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