AFT1 Antibody

1. Taken together, these results suggest that the protein-protein interaction between Sit1 and Aft1 is an important factor in the ferrioxamine B uptake activity of Sit1. PMID: 26323600
2. Aft1p dissociates from its target promoters under iron-replete conditions due to an interaction between Aft1p and the monothiol glutaredoxin Grx3p or Grx4p (Grx3/4p). PMID: 23045394
3. These data suggest that Aft1p and Mac1p might corporately regulate transcription of CTR2. PMID: 22683637
4. investigation of role of Aft-1 (and YAH1) in regulation of iron metabolism under various growth conditions (e.g., low iron in media) PMID: 21361388
5. Aft1/Aft2 activation of the iron regulon depends on mitochondrial but not cytosolic iron-sulfur protein biogenesis PMID: 15649888
6. different cis-regulatory elements are found for Aft1 and Aft2, and transcription analysis indicates that Aft1 is more specific for the canonical iron-responsive element TGCACCC than is Aft2. PMID: 16024809
7. These findings suggest that cisplatin activates Aft1 through the inhibition of iron uptake into the cells, after which the expression of Aft1 target genes involved in iron uptake might be induced. PMID: 17096368
8. These results suggest that iron induces a conformational change in Aft1p, in which Aft1p Cys291 plays a critical role, and that, in turn, Aft1p is recognized by Msn5p and exported into the cytoplasm in an iron-dependent manner. PMID: 17538022
9. These results suggest that Aft1 interacts with Arn3 and may regulate the ubiquitination of Arn3 in the cytosolic compartment. PMID: 19469713

Show More

Hide All

KEGG: sce:YGL071W

STRING: 4932.YGL071W