AGO1 Antibody

1. AGO1 role in the repair of UV-induced DNA lesions PMID: 28325872
2. Here is described the identification of AGO1 association with polysomes through polysome fractionation on sucrose gradient, preparation of proteins by filtration and concentration, and immunoblotting. PMID: 28608339
3. Sweet potato mild mottle virus P1 interacts with AGO1 and AGO2, but solely interferes with AGO1 function. PMID: 28499009
4. Results suggests that ARGONAUTE1 (AGO1) interacts with chromatin at microRNAs MIR161 and MIR173 loci and causes the disassembly of the transcriptional complex, releasing short and unpolyadenylated transcripts. PMID: 27385819
5. that AGO1 may have functions in gene regulation independent of small RNAs. PMID: 27208258
6. AGO1 is a major, largely HSP90-independent, factor in providing environmental robustness to plants. PMID: 26872948
7. miR168 is a key miRNA because it regulates the expression of the slicer protein ARGONAUTE1 (AGO1), which catalyzes mRNA cleavage. Interestingly, plant miR168s are highly evolutionarily conserved; however, it is unclear whether MIR168 promoter elements and expression patterns are also conserved. PMID: 27323093
8. a total of 5,123 and 1,399 AGO1-enriched small RNAs, excluding miRNAs, were identified in Arabidopsis thaliana and rice (Oryza sativa), respectively. PMID: 26206233
9. Mungbean yellow mosaic Indian virus AC2 interacts with AGO1 and inhibits its transcript slicing activity in vitro. PMID: 26433748
10. Base pairing at the 15th nucleotide of a miRNA duplex is important for miRNA sorting in both Arabidopsis AGO1 and AGO2. AGO1 tolerates, or prefers, duplexes with central mismatches. PMID: 25406978
11. In the presence of the wild-type allele of AGO1, most of the mas mutations cause a mild or no mutant phenotype on their own, indicating that the ago1-52 mutant may provide a sensitized background for examining the interactions of AGO1. PMID: 24985352
12. AGO1 is required to restrict AGL16-mediated stomatal spacing divisions, an miRNA pathway in addition to ligand-receptor signaling modules. PMID: 24386951
13. methylation is required to protect miRNAs from AGO1-associated HESO1 activity that normally uridylates 5' fragments. PMID: 24733911
14. a selective process such as ubiquitylation can lead to the degradation of a key regulatory protein such as AGO1 by a degradation process generally believed to be unspecific PMID: 23019378
15. The contrasted effects of viral RNA silencing suppressors on siRNA versus miRNA loading into Argonaute1 imply the existence of two distinct pools of cellular Argonaute1 that are specifically loaded by each class of RNAs. PMID: 22531783
16. EMA1 modulates miRNA activity by influencing the loading of miRNAs into AGO1 complexes. PMID: 21984696
17. Transcriptional elevation of MIR168a is required for maintaining a stable AGO1 transcript level during the stress response. PMID: 22247272
18. P0 protein is a silencing suppressor which inhibits local and systemic RNA silencing through AGO1 degradation. PMID: 22361475
19. provide evidence that AGO1 is a peripheral membrane protein. Moreover, specific hypomorphic mutant alleles of AGO1 display compromised membrane association and AGO1-membrane interaction is reduced upon knockdown of HMG1/MAD3 PMID: 22247288
20. DNA-dependent RNA polymerase V-dependent smRNAs were 21 nt and bound to AGO1, suggesting the potential involvement of AGO1 in Pol V-related pathways. PMID: 21457371
21. The P38 GW residues bind directly and specifically to Arabidopsis AGO1, which, in addition to its role in endogenous microRNA-mediated silencing, is identified as a major effector of TCV-derived siRNAs PMID: 20439431
22. Stduies indicate that RNA silencing can be transmitted between cells through AGO1. PMID: 19822452
23. Thus, we suggest that ARF17 negatively regulates adventitious root formation in ago1 mutants by repressing GH3 genes and therefore perturbing auxin homeostasis in a light-dependent manner PMID: 15829601
24. AGO1 has a role in meristem formation and identity PMID: 15882589
25. Slicer activity fractionates as a complex of approximately 150 kDa that likely constitutes the ARGONAUTE1 protein and associated RNA without any other proteins [ARGONAUTE1] [AGO1] PMID: 16081530
26. AGO1 is required for repressing several class I KNOTTED1-like homeobox (KNOX) genes in leaves, and for specifying both adaxial and abaxial identities of the leaf and petal. PMID: 16786292
27. Genetic supprsesion blocks AGO1 cleavage activity to inhibit miRNA pathways, attenuate RNA silencing, and counter host defense PMID: 17158744
28. miR173 functions in association with AGO1 during TAS1 and TAS2 tasiRNA formation, and data indicates that the miR173-AGO1 complex possesses unique functionality that many other miRNA-AGO1 complexes lack. PMID: 19066226
29. Loss of function of AGO1 perturbed the radial symmetry of Arabidopsis root ground tissue. PMID: 19188262
30. Data show that siRNA-mediated AGO1 silencing depends on correct miRNA targeting, pointing to coordinated regulatory actions of the miRNA and siRNA pathways during the maintenance of AGO1 homeostasis. PMID: 19343050
31. results suggest that 22-nt miR168 ensures basal cleavage of AGO1 mRNA whereas 21-nt miR168 permits an effective response to endogenous or environmental fluctuations owing to its preferential stabilization by AGO1 PMID: 19649244

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KEGG: ath:AT1G48410

STRING: 3702.AT1G48410.2

UniGene: At.21124