ahpC Antibody

Code CSB-PA360037XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) ahpC Polyclonal antibody
Uniprot No.
Target Names
ahpC
Alternative Names
ahpC antibody; b0605 antibody; JW0598 antibody; Alkyl hydroperoxide reductase C antibody; EC 1.11.1.15 antibody; Alkyl hydroperoxide reductase protein C22 antibody; Peroxiredoxin antibody; SCRP-23 antibody; Sulfate starvation-induced protein 8 antibody; SSI8 antibody; Thioredoxin peroxidase antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
A synthesized peptide derived from Escherichia coli (strain K12) ahpC protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, Dot blot (guaranteed specific to the immunizing peptide)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
①. 100ug * KLH-conjugated peptide paired with 100ug * BSA-conjugated peptide (positive control);
②. 1ml*pre-immune serum (used as negative control) for free;
③. Rabbit polyclonal antibodies purified by Antigen Affinity;
Quality Guarantee
1. CUSABIO guarantees the antibody purity > 95% confirmed by SDS-PAGE.
2. CUSABIO guarantees the antibody titer > 1: 64,000 confirmed by ELISA.
3. CUSABIO guarantees to offer Peptide-specific Dot blot.
4. CUSABIO guarantees 100% risk-free: No qualified antibody, no charge.
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Is the primary scavenger for endogenously generated hydrogen peroxides.
Gene References into Functions
  1. a concerted movement involving the NTD, C-terminal NADH, and FAD domains, and the flexible linker between them in AhpF is essential for optimal intra-domain cross-talk and for efficient electron transfer to the redox partner AhpC required for peroxidation PMID: 28270505
  2. Data show that the very C-terminus of the oxidized alkyl hydroperoxide reductase C22 subunit AhpC is oriented away from the dimer interface and away from the catalytic redox-center. PMID: 25193562
  3. AhpC is required for optimal production of enterobactin; data suggested that AhpC affected the activity of EntC or the availability of the chorismate substrate PMID: 23042987
  4. Hpx- (katG katE ahpCF) mutants of Escherichia coli have DNA damage from submicromolar intracellular hydrogen peroxide PMID: 15967999
Subcellular Location
Cytoplasm.
Protein Families
Peroxiredoxin family, AhpC/Prx1 subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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