ahpC Antibody

Code CSB-PA360037XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) ahpC Polyclonal antibody
Uniprot No.
Target Names
ahpC
Alternative Names
ahpC antibody; b0605 antibody; JW0598 antibody; Alkyl hydroperoxide reductase C antibody; EC 1.11.1.15 antibody; Alkyl hydroperoxide reductase protein C22 antibody; Peroxiredoxin antibody; SCRP-23 antibody; Sulfate starvation-induced protein 8 antibody; SSI8 antibody; Thioredoxin peroxidase antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) ahpC protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Is the primary scavenger for endogenously generated hydrogen peroxides.
Gene References into Functions
  1. a concerted movement involving the NTD, C-terminal NADH, and FAD domains, and the flexible linker between them in AhpF is essential for optimal intra-domain cross-talk and for efficient electron transfer to the redox partner AhpC required for peroxidation PMID: 28270505
  2. Data show that the very C-terminus of the oxidized alkyl hydroperoxide reductase C22 subunit AhpC is oriented away from the dimer interface and away from the catalytic redox-center. PMID: 25193562
  3. AhpC is required for optimal production of enterobactin; data suggested that AhpC affected the activity of EntC or the availability of the chorismate substrate PMID: 23042987
  4. Hpx- (katG katE ahpCF) mutants of Escherichia coli have DNA damage from submicromolar intracellular hydrogen peroxide PMID: 15967999
Subcellular Location
Cytoplasm.
Protein Families
Peroxiredoxin family, AhpC/Prx1 subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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