ahr-1 Antibody

Code CSB-PA527364XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans ahr-1 Polyclonal antibody
Uniprot No.
Target Names
ahr-1
Alternative Names
ahr-1 antibody; C41G7.5Aryl hydrocarbon receptor protein 1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans ahr-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Probable ligand-activated transcriptional activator. Acts as a transcriptional regulator in GABAergic motor neuron cell fate specification and development. Promotes cell-type-specific expression of guanylate cyclase genes that have key roles in aggregation behavior and hyperoxia avoidance. Has no role in carbon dioxide avoidance.
Gene References into Functions
  1. These results extend previous studies demonstrating control of gcy family gene expression by AHR-1, and furthermore suggest a role of AHR-1 in regulation of a neuropeptide gene as well as pseudogenes. PMID: 24463456
  2. aha-1 and ahr-1 act genetically upstream of cam-1. CAM-1, a membrane-bound receptor tyrosine kinase, is present on both BDU and PLM cells and likely serves as a Wnt antagonist PMID: 23825972
  3. Fatty acid composition and gene expression profiles are altered in ahr-1 mutant. PMID: 20045492
  4. Results suggest that the aryl hydrocarbon receptor-1 transcriptional complex acts in combination with other intrinsic and extracellular factors to direct the differentiation of distinct neuronal subtypes. PMID: 15136141
  5. We conclude that the AHR-1:AHA-1 transcription complex regulates the expression of soluble guanylate cyclase genes and other unidentified genes that are essential for acute regulation of aggregation behavior. PMID: 16919260

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Subcellular Location
Nucleus.
Tissue Specificity
Expressed in many distinct neuronal cells including RMED, RMEV, RMEL and RMER. Functions in URX neurons to promote aggregation behavior.
Database Links

KEGG: cel:CELE_C41G7.5

STRING: 6239.C41G7.5a

UniGene: Cel.19551

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