aidB Antibody

Code CSB-PA329241XA01ENV
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) aidB Polyclonal antibody
Uniprot No.
Target Names
aidB
Alternative Names
aidB antibody; b4187 antibody; JW5867Putative acyl-CoA dehydrogenase AidB antibody; EC 1.3.99.- antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) aidB protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Part of the adaptive DNA-repair response to alkylating agents. Could prevent alkylation damage by protecting DNA and destroying alkylating agents that have yet to reach their DNA target. Binds to double-stranded DNA with a preference for a DNA region that includes its own promoter. Shows weak isovaleryl-CoA dehydrogenase activity in vitro.
Gene References into Functions
  1. AidB exhibits several discrepancies from ACADs that suggest a novel catalytic mechanism distinct from that of the ACAD family enzymes. PMID: 23443126
  2. AidB was found to bind to RNA, raising the prospect that the protein may have a role in protection of RNA from chemical alkylation. PMID: 21782785
  3. The N-terminal region, comprising the first 439 amino acids possesses dehydrogenase activity, while its C-terminal domain, corresponding to residues 440 to 541 displays DNA binding activity and can negatively regulate the expression of its own gene. PMID: 20889740
  4. AidB is shown to possess flavin adenine dinucleotide (FAD), low levels of isovaleryl-coenzyme A (CoA) dehydrogenase activity, and ability to bind DNA, and is predicted to catalyze the direct repair of alkylated DNA PMID: 16352838
  5. a 1.7-A crystal structure of AidB, which bears superficial resemblance to the acyl-CoA dehydrogenase superfamily of flavoproteins PMID: 18829440

Show More

Hide All

Subcellular Location
Cytoplasm.
Protein Families
Acyl-CoA dehydrogenase family
Database Links
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1