Name: jub Antibody
Brand: CUSABIO
SKU: CSB-PA893347XA01DLU

Product Details

Full Product Name	Rabbit anti-Drosophila melanogaster (Fruit fly) jub Polyclonal antibody
Uniprot No.	Q9VY77
Target Names	jub
Alternative Names	jub antibody; CG11063 antibody; LIM domain-containing protein jub antibody
Raised in	Rabbit
Species Reactivity	Drosophila melanogaster (Fruit fly)
Immunogen	Recombinant Drosophila melanogaster (Fruit fly) jub protein
Immunogen Species	Drosophila melanogaster (Fruit fly)
Conjugate	Non-conjugated
Clonality	Polyclonal
Isotype	IgG
Purification Method	Protein A/G
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Tested Applications	ELISA, WB (ensure identification of antigen)
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables	① 200ug * antigen (positive control); ② 1ml * Pre-immune serum (negative control);
Quality Guarantee	① Antibody purity can be guaranteed above 90% by SDS-PAGE detection; ② ELISA titer can be guaranteed 1: 64,000; ③ WB validation with antigen can be guaranteed positive;
Lead Time	Made-to-order (14-16 weeks)

Target Background

Function (From Uniprot)	Regulates organ size by inhibiting apoptosis and promoting cell proliferation by influencing the expression of G1/S-specific cyclin-E (CycE) and apoptosis 1 inhibitor (th). Negatively regulates the Hippo signaling pathway.
Gene References into Functions	Study reports that increasing tension within the cytoskeleton increases Drosophila wing growth, whereas decreasing cytoskeletal tension decreases wing growth; Jub associates with alpha-catenin and that its localization to adherens junctions and association with alpha-catenin are promoted by cytoskeletal tension. Jub recruits Warts to junctions in a tension-dependent manner. PMID: 24995985 A molecular mechanism linking JNK activity to Yki regulation. JNK can promote YAP activity in mammalian cells. PMID: 24023255 Mutation in jub leads to centrosome separation defects and aberrant mitotic spindles. PMID: 21402878
Subcellular Location	Cell junction, adherens junction.
Protein Families	Zyxin/ajuba family
Database Links	KEGG: dme:Dmel_CG11063 STRING: 7227.FBpp0073665

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jub Antibody

Code	CSB-PA893347XA01DLU
Size	Enquire
Have Questions?	Leave a Message or Start an on-line Chat