Akh Antibody

1. Data (including data from studies using transgenic and mutant strains) suggest that Akh plays role in control of energy metabolism in this species; lipids appear to be main energy reserve during starvation; once glycogen stores are exhausted, carbohydrates are synthesized from other sources. PMID: 30110658
2. During adulthood, however, AKH regulates body fat content and the hemolymph sugar level as well as nutritional and oxidative stress responses. Finally, we provide evidence for a negative autoregulatory loop in Akh gene regulation. PMID: 26275422
3. Akh is an important regulator of metabolic homeostasis in Drosophila PMID: 25641265
4. AKH signaling is required in insulin-producing cells for sugar-dependent Dilp3 release. PMID: 25882208
5. Data (including data from studies using transgenic flies) suggest that FoxO (forkhead box sub-group O) acts downstream of AKH (adipokinetic hormone) as transcription factor to mediate response to oxidative stress. PMID: 25814322
6. Molecular identification of the insect adipokinetic hormone receptors PMID: 11904407
7. Identification of G protein-coupled receptors for Drosophila supports a theory of ligand-receptor coevolution. PMID: 12177421
8. AKH has a role in the regulation of starvation-induced foraging behavior PMID: 15166157

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KEGG: dme:Dmel_CG1171

STRING: 7227.FBpp0073069

UniGene: Dm.23971