ALG3 Antibody

Datasheet

Code	CSB-PA846090XA01HU
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Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ALG3 Polyclonal antibody

Uniprot No.

Q92685

Target Names

ALG3

Alternative Names

ALG3 antibody; NOT antibody; NOT56LDol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase antibody; EC 2.4.1.258 antibody; Asparagine-linked glycosylation protein 3 homolog antibody; Dol-P-Man-dependent alpha(1-3)-mannosyltransferase antibody; Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase antibody; Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase antibody; Not56-like protein antibody

Raised in

Rabbit

Species Reactivity

Homo sapiens (Human)

Immunogen

Recombinant Homo sapiens (Human) ALG3 protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man5GlcNAc2-PP-Dol.

Gene References into Functions

Silencing ALG3 or HSF2 inhibited the proliferation, migration, and invasion abilities of MCF-7 cells. PMID: 29799832
ALG3-CDG is due to an autosomal recessive defect in the ER mannosyl-transferase VI, which is involved in protein N-glycosylation. The enzyme is encoded by the ALG3 gene PMID: 23791010
a mutation in ALG3 affects splicing and may have a role in development of congenital disorder of glycosylation type Id [case report] PMID: 16006436

Involvement in disease

Congenital disorder of glycosylation 1D (CDG1D)

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Protein Families

Glycosyltransferase 58 family

Database Links

HGNC: 23056

OMIM: 601110

KEGG: hsa:10195

STRING: 9606.ENSP00000380793

UniGene: Hs.478481

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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ALG3 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background