ALKBH2 Antibody

Code CSB-PA566004XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ALKBH2 Polyclonal antibody
Uniprot No.
Target Names
ALKBH2
Alternative Names
ALKBH2 antibody; At2g22260 antibody; T26C19.8DNA oxidative demethylase ALKBH2 antibody; EC 1.14.11.33 antibody; Alkylated DNA repair protein alkB homolog 2 antibody; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana ALKBH2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Dioxygenase that repairs alkylated DNA containing 1-methyladenine and 1-ethenoadenine by oxidative demethylation. Accepts double-stranded and single-stranded substrates, with a preference for dsDNA over ssDNA. Confers resistance to methylating agents such as methylmethanesulphonate (MMS).
Gene References into Functions
  1. The present study establishes ALKBH2 as an important enzyme for protecting Arabidopsis against methylation damage in DNA. PMID: 22532610
Subcellular Location
Nucleus.
Protein Families
AlkB family
Tissue Specificity
Expressed ubiquitously, including in seedlings, leaves and flowers.
Database Links

KEGG: ath:AT2G22260

STRING: 3702.AT2G22260.1

UniGene: At.39463

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