ani-2 Antibody

Code CSB-PA600294XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans ani-2 Polyclonal antibody
Uniprot No.
Target Names
ani-2
Alternative Names
ani-2 antibody; K10B2.5Anillin-like protein 2 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans ani-2 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required to maintain the structure of the rachis, the central cytoplasmic core of the syncytial adult gonad. Failure to maintain the rachis leads to premature dissociation of oocytes and thereby impedes oogenesis.
Gene References into Functions
  1. ANI-2 promotes germ cell syncytial organization and allows for compensation of the mechanical stress associated with oogenesis. PMID: 24982432
  2. These results indicate that PAR-4 controls C. elegans embryonic polarity by regulating the activity of anillin family scaffold proteins, thus enabling turnover of cortical myosin and efficient actomyosin contractility. PMID: 21276723
Tissue Specificity
Localizes to the surface of the rachis.
Database Links

KEGG: cel:CELE_K10B2.5

STRING: 6239.K10B2.5

UniGene: Cel.23022

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