AOC2 Antibody

Code CSB-PA001854ZA01HU
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) AOC2 Polyclonal antibody
Uniprot No. O75106
Target Names AOC2
Alternative Names Amine oxidase [copper containing] antibody; Amine oxidase [copper-containing] antibody; Amine oxidase copper containing 2 (retina specific) antibody; Amine oxidase copper containing 2 antibody; AOC2 antibody; AOC2_HUMAN antibody; DAO2 antibody; RAO antibody; Retina specific copper amine oxidase antibody; Retina-specific copper amine oxidase antibody; Semicarbazide-sensitive amine oxidase antibody; SSAO antibody
Raised in Rabbit
Species Reactivity Homo sapiens
Immunogen Recombinant Human Retina-specific copper amine oxidase (AOC2) (33-756AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Made-to-order

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Target Data

Function Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulator of signal transmission in retina.
Gene References into Functions
  1. Adipose tissue SSAO activity did not vary according to anatomical location and/or metabolic status in severely obese women. PMID: 27766585
  2. AOC2 mRNA is expressed in many tissues, however, the only tissues with detectable AOC2-like enzyme activity is found in the eye. PMID: 19588076
Subcellular Location Isoform 1: Cell membrane, Peripheral membrane protein, Note=Present on the surface of the cells, SUBCELLULAR LOCATION: Isoform 2: Cytoplasm
Protein Families Copper/topaquinone oxidase family
Tissue Specificity Expressed in many tissues with much higher expression in retina. Isoform 1 and isoform 2 are expressed in adipose tissue, whereas isoform 1 only seems to be present in thymus, and isoform 2 only in testis.
Database Links

HGNC: 549

OMIM: 602268

KEGG: hsa:314

STRING: 9606.ENSP00000253799

UniGene: Hs.143102

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