AOC2 Antibody

Code CSB-PA001854ZA01HU
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) AOC2 Polyclonal antibody
Uniprot No.
Target Names
AOC2
Alternative Names
Amine oxidase [copper containing] antibody; Amine oxidase [copper-containing] antibody; Amine oxidase copper containing 2 (retina specific) antibody; Amine oxidase copper containing 2 antibody; AOC2 antibody; AOC2_HUMAN antibody; DAO2 antibody; RAO antibody; Retina specific copper amine oxidase antibody; Retina-specific copper amine oxidase antibody; Semicarbazide-sensitive amine oxidase antibody; SSAO antibody
Raised in
Rabbit
Species Reactivity
Homo sapiens
Immunogen
Recombinant Homo sapiens AOC2 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulator of signal transmission in retina.
Gene References into Functions
  1. Adipose tissue SSAO activity did not vary according to anatomical location and/or metabolic status in severely obese women. PMID: 27766585
  2. AOC2 mRNA is expressed in many tissues, however, the only tissues with detectable AOC2-like enzyme activity is found in the eye. PMID: 19588076
Subcellular Location
[Isoform 1]: Cell membrane; Peripheral membrane protein.; [Isoform 2]: Cytoplasm.
Protein Families
Copper/topaquinone oxidase family
Tissue Specificity
Expressed in many tissues with much higher expression in retina. Isoform 1 and isoform 2 are expressed in adipose tissue, whereas isoform 1 only seems to be present in thymus, and isoform 2 only in testis.
Database Links

HGNC: 549

OMIM: 602268

KEGG: hsa:314

STRING: 9606.ENSP00000253799

UniGene: Hs.143102

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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