unc-101 Antibody

Datasheet

Code	CSB-PA120457XA01CXY
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans unc-101 Polyclonal antibody

Uniprot No.

P35602

Target Names

unc-101

Alternative Names

unc-101 antibody; K11D2.3 antibody; AP-1 complex subunit mu-1-I antibody; Clathrin assembly protein complex 1 mu-1-I medium chain antibody; Clathrin coat assembly protein AP47 antibody; Clathrin coat-associated protein AP47 antibody; Golgi adaptor AP-1 47 kDa protein antibody; HA1 47 kDa subunit antibody; Mu1-I-adaptin antibody; Uncoordinated protein 101 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans unc-101 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of the adaptor complexes which link clathrin to receptors in coated vesicles (Probable). Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (Probable). Required for many aspects of development and behavior, including negative regulation of vulval differentiation. Required for the dendritic localization of potassium channel kvs-4 in the cholinergic motor neuron DA9.

Gene References into Functions

Data suggest UNC-101/AP-1 mu1 subunit exhibits a novel bipartite sorting signal within KVS-4/Kv2.1 consisting of C-terminal EQMIL and N-terminal WNIIE motifs; such sorting signals appear to account for somatodendritic distribution of KVS-4/Kv2.1. PMID: 26762178
An AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 basolateral localization and signaling during C. elegans vulva induction. PMID: 25329472

Subcellular Location

Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, dendrite.

Protein Families

Adaptor complexes medium subunit family

Tissue Specificity

Expressed in the cholinergic motor neuron DA9.

Database Links

KEGG: cel:CELE_K11D2.3

STRING: 6239.K11D2.3a.1

UniGene: Cel.19746

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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