APS1 Antibody

Code CSB-PA339538XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) APS1 Polyclonal antibody
Uniprot No.
Target Names
APS1
Alternative Names
APS1 antibody; YAP19 antibody; YLR170C antibody; L9470.16AP-1 complex subunit sigma-1 antibody; Clathrin assembly protein complex 1 sigma-1 small chain antibody; Clathrin coat assembly protein AP19 antibody; Clathrin coat-associated protein AP19 antibody; Golgi adaptor AP-1 19 kDa adaptin antibody; HA1 19 kDa subunit antibody; Sigma1-adaptin antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) APS1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP19 is probably a subunit of the Golgi membrane adapter. Component of the AP-1-related (AP-1R) complex, an adapter protein complex that mediates sorting of cargo SNARE SNC1. In contrast to the APM1-containing AP-1 complex, AP-1R is incapable of sorting CHS3.
Gene References into Functions
  1. Drs2p acts independently of coat recruitment to facilitate AP-1/clathrin-coated vesicle budding from the TGN PMID: 18508916
Subcellular Location
Cytoplasm. Nucleus. Cytoplasmic vesicle, clathrin-coated vesicle membrane. Endosome. Golgi apparatus.
Protein Families
Adaptor complexes small subunit family
Database Links

KEGG: sce:YLR170C

STRING: 4932.YLR170C

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