apn-1 Antibody

Code CSB-PA611897XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans apn-1 Polyclonal antibody
Uniprot No.
Target Names
apn-1
Alternative Names
apn-1 antibody; T05H10.2DNA-(apurinic or apyrimidinic site) lyase antibody; EC 4.2.99.18 antibody; Apurinic-apyrimidinic endonuclease antibody; AP endonuclease antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans apn-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Gene References into Functions
  1. Purified APN-1 displays AP endonuclease activity, 3'-diesterase activity, 3'- to 5'-exonuclease activity and the nucleotide incision repair activity. PMID: 22819077
  2. results show that apurinic/apyrimidinic endonuclease 1/EXO-3, p53/CEP-1, and thioredoxin affect each other and that these interactions determine aging as well as neuronal structure and function PMID: 20346071
  3. APN-1 is an important apurinic/apyrimidinc endonuclease for repair of misincorporated uracil. PMID: 20036200
  4. Apn-1 expresses apurinic/apyrimidinic endonuclease in a Saccharomyces cerevisiae mutant. PMID: 15907773
Subcellular Location
Nucleus.
Protein Families
AP endonuclease 2 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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