Arf51F Antibody

Code CSB-PA001990XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Arf51F Polyclonal antibody
Uniprot No.
Target Names
Arf51F
Alternative Names
Arf51F antibody; Arf3 antibody; Arf6 antibody; CG8156 antibody; ADP-ribosylation factor 6 antibody; ARF6 antibody; ADP ribosylation factor at 51F antibody; ADP-ribosylation factor 3 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Arf51F protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Promotes cell movement and remodeling of the actin cytoskeleton during compound eye morphogenesis. Required for normal ethanol-induced tolerance and preference. Probably after Efa6-mediated activation, counteracts ethanol-induced sedation.
Gene References into Functions
  1. EGFR/ARF6 regulation of Hh signaling stimulates oncogenic Ras tumor overgrowth in Drosophila. PMID: 28281543
  2. We show that Arf6 functions in the adult nervous system to control ethanol-induced behavior. PMID: 23223291
  3. Cindr-mediated regulation of Arf6 is a widely used mechanism in emerging epithelia. PMID: 21976699
  4. ARF6 promotes rapid recycling of endosomal membrane stores during spermatocyte cytokinesis, which is critical for rapid cleavage furrow ingression. PMID: 18039970
Subcellular Location
Golgi apparatus.
Protein Families
Small GTPase superfamily, Arf family
Tissue Specificity
Expressed in the head (at protein level).
Database Links

KEGG: dme:Dmel_CG8156

STRING: 7227.FBpp0086507

UniGene: Dm.2891

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