ARR3 Antibody

Code CSB-PA213626XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ARR3 Polyclonal antibody
Uniprot No.
Target Names
ARR3
Alternative Names
ARR3 antibody; ACR3 antibody; YPR201W antibody; P9677.2 antibody; Arsenical-resistance protein 3 antibody; Arsenic compounds resistance protein 3 antibody; As(III)/H(+) and Sb(III)/H(+)antiporter antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ARR3 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Plasma membrane transporter that confers resistance to toxic metalloids by mediating extrusion of arsenite (As(III)) and antimonite (Sb(III)) out of cells. Displays low-affinity As(III)/H(+) and Sb(III)/H(+) exchange activity.
Gene References into Functions
  1. Transmembrane topology of the arsenite permease Acr3 from Saccharomyces cerevisiae has been reported. PMID: 27836640
  2. study identified several charged/polar and aromatic residues of Acr3p localized in the predicted transmembrane segments of the yeast arsenite transporter Acr3p that are important for As(III)/H+ antiport activity PMID: 26123064
  3. Heterologous expression of yeast ACR3 endows plants with greater arsenic resistance, but does not lower significantly arsenic tissue levels. PMID: 22380876
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
Arsenical resistance-3 (ACR3) (TC 2.A.59) family
Database Links

KEGG: sce:YPR201W

STRING: 4932.YPR201W

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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