ASI1A Antibody

Code CSB-PA765103XA01DIL
Product Type Polyclonal Antibody
Uniprot No. Q708S7
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) ASI1A protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Acid-sensing ion channel 1A (ASIC1-A) (Acid-sensing ion channel 1.2-A) (Amiloride-sensitive cation channel 2-B, neuronal-A) (ZASIC1.2) asic1a accn2b
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names asic1a
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Proton-gated sodium channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions.
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families Amiloride-sensitive sodium channel (TC 1.A.6) family, ASIC1 subfamily
Tissue Specificity Expressed in central nervous system. Faintly expressed in the trunk, presumably in dorsal root ganglia.
Database Links

KEGG: dre:791696

STRING: 7955.ENSDARP00000011782

UniGene: Dr.98481

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