asp Antibody

Datasheet

Code	CSB-PA894202XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) asp Polyclonal antibody

Uniprot No.

Q9VC45

Target Names

asp

Alternative Names

asp antibody; CG6875Protein abnormal spindle antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) asp protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation.

Gene References into Functions

Dynein, Mud and Asp operate sequentially during the cell cycle to ensure efficient centrosome-spindle coupling in mitosis, thereby preventing centrosome mis-segregation to maintain centrosome number. PMID: 28864767
Asp at the minus ends of the microtubules cross-links MTs at the pole and within the spindle PMID: 26644514
propose that Asp regulates neuroepithelium morphogenesis through myosin-II-mediated structural and mechanical processes to maintain force balance and tissue cohesiveness PMID: 24142104
asp mutation leads to severe defects in spindle microtubule organization within the germarium. The mitotic spindles of the mutant cystocytes are composed by wavy microtubules and have abnormal poles that often lack gamma-tubulin. PMID: 15242765

Subcellular Location

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During interphase in syncytial embryos distribution is cytoplasmic. On entering mitosis, moves to polar regions of the spindle immediately surrounding the centrosome. At telophase, migrates to microtubules on the spindle side of both daughter nuclei. The nuclear-cytoplasmic distribution could be regulated by the availability of calmodulin.

Database Links

KEGG: dme:Dmel_CG6875

STRING: 7227.FBpp0084071

UniGene: Dm.7038

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asp Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background