atad-3 Antibody

Code CSB-PA554690XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans atad-3 Polyclonal antibody
Uniprot No.
Target Names
atad-3
Alternative Names
atad-3 antibody; F54B3.3ATPase family AAA domain-containing protein 3 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans atad-3 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. Important during development for the up-regulation of mitochondrial activity during the transition to higher larval stages. Regulates mitochondrial iron homeostasis. May play an important role in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Plays a role in regulating the production of reactive oxygen species in response to heat stress.
Gene References into Functions
  1. ATAD-3 modulates mitochondrial iron and heme homeostasis. PMID: 26427876
Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion matrix, mitochondrion nucleoid.
Protein Families
AAA ATPase family
Database Links

KEGG: cel:CELE_F54B3.3

STRING: 6239.F54B3.3

UniGene: Cel.7679

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